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Fackson Mwale Selected Research

Hypertrophy

7/2015The Effects of Naproxen on Chondrogenesis of Human Mesenchymal Stem Cells.
1/2015Naproxen induces type X collagen expression in human bone-marrow-derived mesenchymal stem cells through the upregulation of 5-lipoxygenase.
7/2014Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules.
4/2013Effect of acetaminophen and nonsteroidal anti-inflammatory drugs on gene expression of mesenchymal stem cells.
1/2011Effect of nitrogen-rich cell culture surfaces on type X collagen expression by bovine growth plate chondrocytes.
1/2011The constitutive expression of type x collagen in mesenchymal stem cells from osteoarthritis patients is reproduced in a rabbit model of osteoarthritis.
11/2010Effect of parathyroid hormone on type X and type II collagen expression in mesenchymal stem cells from osteoarthritic patients.
9/2010Novel insights into the mechanism of decreased expression of type X collagen in human mesenchymal stem cells from patients with osteoarthritis cultured on nitrogen-rich plasma polymers: implication of cyclooxygenase-1.
10/2008The Potential of N-Rich Plasma-Polymerized Ethylene (PPE:N) Films for Regulating the Phenotype of the Nucleus Pulposus.
9/2006Suppression of genes related to hypertrophy and osteogenesis in committed human mesenchymal stem cells cultured on novel nitrogen-rich plasma polymer coatings.
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Fackson Mwale Research Topics

Disease

13Intervertebral Disc Degeneration
01/2022 - 09/2004
13Hypertrophy
07/2015 - 02/2002
9Osteoarthritis
02/2024 - 10/2008
9Pain (Aches)
02/2024 - 04/2013
2Arthritis (Polyarthritis)
06/2023 - 04/2013
2Hyperalgesia
10/2022 - 03/2018
2Osteolysis
07/2006 - 10/2005
1Arthralgia (Joint Pain)
02/2024
1Multiple Sclerosis
06/2023
1Chronic Pain
06/2023
1Fibromyalgia (Fibrositis)
06/2023
1Bone Resorption
01/2021
1Low Back Pain (Lumbago)
01/2020
1Neuralgia (Stump Neuralgia)
03/2018
1Back Pain (Backache)
03/2018
1Relative Energy Deficiency in Sport
12/2012
1Scoliosis
12/2011
1Neoplasms (Cancer)
02/2009
1Hypersensitivity (Allergy)
08/2008
1Necrosis
12/2004

Drug/Important Bio-Agent (IBA)

11Collagen Type XIBA
07/2015 - 10/2005
4Proteoglycans (Proteoglycan)IBA
10/2018 - 02/2002
4Aggrecans (Aggrecan)IBA
06/2013 - 08/2006
4NitrogenIBA
01/2011 - 09/2006
3Nerve Growth Factor (NGF)IBA
01/2024 - 03/2018
3Peptides (Polypeptides)IBA
03/2018 - 09/2014
3MineralsIBA
12/2012 - 02/2002
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2011 - 10/2005
3MetalsIBA
02/2009 - 12/2004
3IonsIBA
02/2009 - 12/2004
2Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
01/2024 - 01/2020
2TropomyosinIBA
01/2024 - 10/2022
2Protein Kinases (Protein Kinase)IBA
01/2024 - 11/2010
2Matrix Metalloproteinase 13IBA
01/2024 - 02/2002
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2024 - 01/2020
2Phosphotransferases (Kinase)IBA
01/2024 - 10/2022
2Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2015
2Dichlorodiphenyldichloroethane (DDD)IBA
01/2020 - 12/2011
2CytokinesIBA
03/2018 - 10/2005
2CollagenIBA
01/2018 - 02/2002
2PolymersIBA
09/2010 - 09/2006
2Collagen Type II (Type II Collagen)IBA
08/2006 - 02/2002
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
02/2024
1Naltrexone (ReVia)FDA LinkGeneric
06/2023
1Narcotic Antagonists (Opioid Antagonists)IBA
06/2023
1Opiate AlkaloidsIBA
06/2023
1Opioid Analgesics (Opioids)IBA
06/2023
1TungstenIBA
01/2021
1Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
01/2020
1Small Interfering RNA (siRNA)IBA
01/2020
1Brain-Derived Neurotrophic Factor (BDNF)IBA
03/2018
1Nerve Growth Factors (Neurotrophins)IBA
03/2018
1Syndecan-4IBA
09/2014
1Naproxen (Naprosyn)FDA LinkGeneric
07/2014
1Alkaline PhosphataseIBA
04/2013
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
04/2013
1Dacarbazine (DIC)FDA LinkGeneric
04/2013
1Acetaminophen (Paracetamol)FDA LinkGeneric
04/2013
1OsteocalcinIBA
04/2013
1Integrin-Binding SialoproteinIBA
04/2013
1Alcian BlueIBA
12/2012
1Parathyroid Hormone (Parathormone)IBA
11/2010
1Cyclooxygenase 1IBA
09/2010
1Biocompatible Materials (Biomaterials)IBA
10/2008
1Collagen Type I (Type I Collagen)IBA
10/2008
1ethyleneIBA
10/2008
1Tissue Inhibitor of Metalloproteinase-1IBA
10/2005
1Fibrillar CollagensIBA
10/2005
1Polypropylenes (Polypropylene)IBA
10/2005
1Peptide Hydrolases (Proteases)FDA Link
10/2005
1nylon 6 (Perlon)IBA
10/2005
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2005
1GlycosaminoglycansIBA
09/2004
1Collagenases (Collagenase)FDA Link
02/2002

Therapy/Procedure

6Therapeutics
03/2018 - 06/2013
2Meniscectomy
02/2024 - 10/2022
1Intra-Articular Injections
02/2024
1Punctures
01/2018
1Biological Therapy
06/2013
1Hip Replacement Arthroplasty (Total Hip Replacement)
07/2006